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The ‘Biggest Breakthrough’ so far in the Treatment of Corona



The injectable drug is called dexamethasone and is being developed by dozens of companies in Pakistan (AFP).

Experts say the most significant progress has been made so far in saving the lives of coronavirus patients, and a common drug has been found to be effective in treating the disease.

The drug is called dexamethasone and is being manufactured by dozens of companies in Pakistan, and costs around Rs 300.

This medicine has been used for a long time for joint pain, allergies and asthma.

A medical trial conducted by the University of Oxford in the United Kingdom found that 2,100 patients with Wood 19 had a 30 percent lower mortality rate than those who used a ventilator. However, in patients who were given only oxygen, the mortality rate dropped to 20%. However, no significant benefit was found in patients with coronary heart disease.

Oxford scientists say that if this drug had been known to be so effective, 5,000 lives could have been saved in the UK alone.

dexamethasone

Matt Hancock, Britain’s health minister, tweeted about the findings: “This is the world’s first example of the power of science.” I’m so glad we can announce the first successful trial of Wood 19 treatment.

The information comes from a trial called “Recovery”, which was launched in the UK in March and involved more than 11,000 patients in 175 hospitals. Details can be seen here.

“This is a significant development in many ways,” lead researcher Martin Landre told the British newspaper The Telegraph. Before the outbreak began six months ago, there was a search for a cure that would reduce the risk of death, but no cure had been found. Got it now.

“The results are clear and therefore the drug might be given to patients from tonight.

This is a really important step. ‘

“This medicine isn’t very expensive, neither is it a drug that takes time to provide or prepare,” he added.

The British Department of Health NHS has already instructed hospitals to use the drug.

NHS Medical Director Professor Steven Powell said:

This is a significant breakthrough in discovering a cure for Wood’s patients, not only in the UK but around the world.

How does dexamethasone work?

Coronavirus virus is known to cause the human body’s immune system to become more active than necessary by sensing the danger of the virus and starting to harm the body itself. It has a major effect on the lungs and critically ill patients cannot breathe. This process is called ‘cytokine storm’.

Apparently most patients do not die from the virus, but rather die from the body’s severe reaction to the virus.

Dexamethasone is a steroid and was first developed in 1957 and approved for treatment in 1961. It is a drug that controls the release of harmful substances by the body’s immune system. It also reduces inflammation.

Another important point is that dexamethasone is not a new drug but has been given to millions of people for the last 59 years, so there is already information about its side effects.

Details of the study are available on the Recovery Trial website, and the study has not yet been published in a medical journal. Scientists say that given the importance of this research, they are publishing the results on the website immediately, while it may take time to publish in the journal.

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